Educational content for trained professionals. Not a Safety Data Sheet, not medical advice. In an emergency, call your local poison control or emergency services immediately. Terms of use.
2,4-Dinitrophenol
Also known as: 2,4-dinitrophenol · 51-28-5 · Aldifen · Nitrophene
- CAS No.
- 51-28-5
- Formula
- C6H4N2O5
- Molar mass
- 184.11 g/mol
- PubChem CID
- 1493
Explosive
Toxic
Harmful / Irritant
Health hazard
Environmental hazard
Summary
2,4-Dinitrophenol (C6H4N2O5), CAS 51-28-5. Common in labs and industry. Read on for hazards, storage, PPE and mixing rules.
Background
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Hazards
May explode when exposed to heat, shock or flame.
May be fatal even in small doses.
May cause skin, eye or respiratory irritation.
Serious long-term health effects (CMR, respiratory sensitizer).
Toxic to aquatic organisms.
Hazard statements
- H300: Fatal if swallowed [Danger Acute toxicity, oral]
- H311: Toxic in contact with skin [Danger Acute toxicity, dermal]
- H331: Toxic if inhaled [Danger Acute toxicity, inhalation]
- H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
- H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
- H201: (Deleted) Explosive
- H301
- H373
- H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
- H310: Fatal in contact with skin [Danger Acute toxicity, dermal]
- H315: Causes skin irritation [Warning Skin corrosion/irritation]
- H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]
- H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
- H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]
Storage
Keep at room temperature, below 30 °C, out of direct heat.
Store somewhere well-ventilated and away from any ignition source.
Metal drums or tinted glass, tightly sealed.
Strong acids, strong bases and powerful oxidizers.
Personal protective equipment
Nitrile or butyl, at least 0.4 mm thick.
Safety goggles with side shields.
A2 organic-vapor cartridge if the room isn't well ventilated.
Occupational exposure limits (HSE)
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EU harmonised classification (ECHA C&L)
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Transport
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FDA recalls & enforcement
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Compatibilities
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Open comparator with 2,4-DinitrophenolPractical safety notes
- Explosive. Keep away from shock, friction, sparks and heat. Store in dedicated magazines.
- Acute toxicity. Work under a fume hood, restrict access, keep a specific antidote plan available.
- Irritant / harmful. Ventilate the workspace and avoid skin contact.
- Serious health hazard (carcinogen, mutagen, reprotoxic, respiratory sensitizer). Substitute if possible; otherwise closed systems and medical surveillance.
- Environmental hazard. Do not release to sewers or waterways; collect for hazardous waste disposal.
Derived from the GHS classification shown above. These notes are generic guidance and do not replace the manufacturer's SDS or your local risk assessment.
FAQ
Is 2,4-Dinitrophenol flammable?+
2,4-Dinitrophenol (CAS 51-28-5) does not carry the GHS02 flame pictogram in our records. Always confirm with the manufacturer's SDS section 9 (flash point) before assuming a product is non-flammable.
What PPE should I wear when handling 2,4-Dinitrophenol?+
Safety glasses with side shields and nitrile gloves are the baseline. Work inside a fume hood or use a suitable respirator. Check SDS section 8 for material-specific breakthrough times.
How should 2,4-Dinitrophenol be stored?+
Store 2,4-Dinitrophenol (CAS 51-28-5) in tightly closed original containers, in a cool, dry, well-ventilated area away from incompatible materials.
Is 2,4-Dinitrophenol dangerous for the environment?+
Yes. 2,4-Dinitrophenol carries the GHS09 environment pictogram. Do not release to drains, soil or waterways; collect residues for hazardous-waste disposal in line with local regulations.
Where can I find the official Safety Data Sheet for 2,4-Dinitrophenol?+
Official, up-to-date SDS documents are published by each manufacturer (Sigma-Aldrich, Merck, Thermo Fisher, VWR, Carl Roth, etc.) and by regulators such as ECHA and NIOSH. This page is an educational summary and does not replace the manufacturer's SDS.
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