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2-Chloro-1,1,1-trifluoroethane

Also known as: 2-Chloro-1,1,1-trifluoroethane · 75-88-7 · HCFC-133a · 1,1,1-TRIFLUORO-2-CHLOROETHANE

CAS No.: 75-88-7
Formula: C2H2ClF3
Molar mass: 118.48 g/mol
PubChem CID: 6408

GHS pictograms

Compressed gas

Harmful / Irritant

Health hazard

2D structure of 2-Chloro-1,1,1-trifluoroethane — 2D structure · PubChem CID 6408

Summary

2-Chloro-1,1,1-trifluoroethane (C2H2ClF3), CAS 75-88-7. Common in labs and industry. Read on for hazards, storage, PPE and mixing rules.

Background

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Hazards

Compressed gas (GHS04)

Contents under pressure, may explode if heated.

Harmful / Irritant (GHS07)

May cause skin, eye or respiratory irritation.

Health hazard (GHS08)

Serious long-term health effects (CMR, respiratory sensitizer).

Hazard statements

H280: Contains gas under pressure
H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure
H360: May damage fertility or the unborn child [Danger Reproductive toxicity]

Storage

Temperature

Keep at room temperature, below 30 °C, out of direct heat.

Ventilation

Store somewhere well-ventilated and away from any ignition source.

Containers

Metal drums or tinted glass, tightly sealed.

Keep away from

Strong acids, strong bases and powerful oxidizers.

Personal protective equipment

Gloves

Nitrile or butyl, at least 0.4 mm thick.

Eye protection

Safety goggles with side shields.

Respirator

A2 organic-vapor cartridge if the room isn't well ventilated.

Occupational exposure limits (HSE)

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EU harmonised classification (ECHA C&L)

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Transport

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FDA recalls & enforcement

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Compatibilities

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Practical safety notes

Compressed gas. Secure cylinders upright, protect valves, store in ventilated areas.
Irritant / harmful. Ventilate the workspace and avoid skin contact.
Serious health hazard (carcinogen, mutagen, reprotoxic, respiratory sensitizer). Substitute if possible; otherwise closed systems and medical surveillance.

Derived from the GHS classification shown above. These notes are generic guidance and do not replace the manufacturer's SDS or your local risk assessment.

FAQ

Is 2-Chloro-1,1,1-trifluoroethane flammable?+

2-Chloro-1,1,1-trifluoroethane (CAS 75-88-7) does not carry the GHS02 flame pictogram in our records. Always confirm with the manufacturer's SDS section 9 (flash point) before assuming a product is non-flammable.

What PPE should I wear when handling 2-Chloro-1,1,1-trifluoroethane?+

Safety glasses with side shields and nitrile gloves are the baseline. Work inside a fume hood or use a suitable respirator. Check SDS section 8 for material-specific breakthrough times.

How should 2-Chloro-1,1,1-trifluoroethane be stored?+

Store 2-Chloro-1,1,1-trifluoroethane (CAS 75-88-7) in tightly closed original containers, in a cool, dry, well-ventilated area away from incompatible materials.

Is 2-Chloro-1,1,1-trifluoroethane dangerous for the environment?+

No specific environmental pictogram (GHS09) is listed in our records for 2-Chloro-1,1,1-trifluoroethane, but any chemical waste should be handled through your site's hazardous-waste procedure, not poured down the drain.

Where can I find the official Safety Data Sheet for 2-Chloro-1,1,1-trifluoroethane?+

Official, up-to-date SDS documents are published by each manufacturer (Sigma-Aldrich, Merck, Thermo Fisher, VWR, Carl Roth, etc.) and by regulators such as ECHA and NIOSH. This page is an educational summary and does not replace the manufacturer's SDS.

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