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2-Methoxyaniline

Also known as: O-ANISIDINE · 2-Methoxyaniline · 90-04-0 · 2-Anisidine

CAS No.
90-04-0
Formula
C7H9NO
Molar mass
123.15 g/mol
PubChem CID
7000
GHS pictograms
GHS pictogram: ToxicToxic
GHS pictogram: Harmful / IrritantHarmful / Irritant
GHS pictogram: Health hazardHealth hazard
GHS pictogram: Environmental hazardEnvironmental hazard
2D structure of 2-Methoxyaniline
2D structure · PubChem CID 7000

Summary

2-Methoxyaniline (C7H9NO), CAS 90-04-0. Common in labs and industry. Read on for hazards, storage, PPE and mixing rules.

Background

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Hazards

GHS pictogram: Toxic
Toxic (GHS06)

May be fatal even in small doses.

GHS pictogram: Harmful / Irritant
Harmful / Irritant (GHS07)

May cause skin, eye or respiratory irritation.

GHS pictogram: Health hazard
Health hazard (GHS08)

Serious long-term health effects (CMR, respiratory sensitizer).

GHS pictogram: Environmental hazard
Environmental hazard (GHS09)

Toxic to aquatic organisms.

Hazard statements

  • H301: Toxic if swallowed [Danger Acute toxicity, oral]
  • H311: Toxic in contact with skin [Danger Acute toxicity, dermal]
  • H331: Toxic if inhaled [Danger Acute toxicity, inhalation]
  • H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]
  • H350: May cause cancer [Danger Carcinogenicity]
  • H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
  • H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
  • H401: Toxic to aquatic life [Hazardous to the aquatic environment, acute hazard]
  • H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
  • H302: Harmful if swallowed [Warning Acute toxicity, oral]
  • H320: Causes eye irritation [Warning Serious eye damage/eye irritation]
  • H351: Suspected of causing cancer [Warning Carcinogenicity]
  • H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]

Storage

Temperature

Keep at room temperature, below 30 °C, out of direct heat.

Ventilation

Store somewhere well-ventilated and away from any ignition source.

Containers

Metal drums or tinted glass, tightly sealed.

Keep away from

Strong acids, strong bases and powerful oxidizers.

Personal protective equipment

Gloves

Nitrile or butyl, at least 0.4 mm thick.

Eye protection

Safety goggles with side shields.

Respirator

A2 organic-vapor cartridge if the room isn't well ventilated.

Occupational exposure limits (HSE)

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EU harmonised classification (ECHA C&L)

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Transport

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FDA recalls & enforcement

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Compatibilities

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Practical safety notes

  • Acute toxicity. Work under a fume hood, restrict access, keep a specific antidote plan available.
  • Irritant / harmful. Ventilate the workspace and avoid skin contact.
  • Serious health hazard (carcinogen, mutagen, reprotoxic, respiratory sensitizer). Substitute if possible; otherwise closed systems and medical surveillance.
  • Environmental hazard. Do not release to sewers or waterways; collect for hazardous waste disposal.

Derived from the GHS classification shown above. These notes are generic guidance and do not replace the manufacturer's SDS or your local risk assessment.

FAQ

Is 2-Methoxyaniline flammable?+

2-Methoxyaniline (CAS 90-04-0) does not carry the GHS02 flame pictogram in our records. Always confirm with the manufacturer's SDS section 9 (flash point) before assuming a product is non-flammable.

What PPE should I wear when handling 2-Methoxyaniline?+

Safety glasses with side shields and nitrile gloves are the baseline. Work inside a fume hood or use a suitable respirator. Check SDS section 8 for material-specific breakthrough times.

How should 2-Methoxyaniline be stored?+

Store 2-Methoxyaniline (CAS 90-04-0) in tightly closed original containers, in a cool, dry, well-ventilated area away from incompatible materials.

Is 2-Methoxyaniline dangerous for the environment?+

Yes. 2-Methoxyaniline carries the GHS09 environment pictogram. Do not release to drains, soil or waterways; collect residues for hazardous-waste disposal in line with local regulations.

Where can I find the official Safety Data Sheet for 2-Methoxyaniline?+

Official, up-to-date SDS documents are published by each manufacturer (Sigma-Aldrich, Merck, Thermo Fisher, VWR, Carl Roth, etc.) and by regulators such as ECHA and NIOSH. This page is an educational summary and does not replace the manufacturer's SDS.

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