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2-Nitrophenol

Also known as: 2-NITROPHENOL · o-Nitrophenol · 88-75-5 · 2-Hydroxynitrobenzene

CAS No.
88-75-5
Formula
C6H5NO3
Molar mass
139.11 g/mol
PubChem CID
6947
GHS pictograms
GHS pictogram: CorrosiveCorrosive
GHS pictogram: Harmful / IrritantHarmful / Irritant
GHS pictogram: Health hazardHealth hazard
GHS pictogram: Environmental hazardEnvironmental hazard
2D structure of 2-Nitrophenol
2D structure · PubChem CID 6947

Summary

2-Nitrophenol (C6H5NO3), CAS 88-75-5. Common in labs and industry. Read on for hazards, storage, PPE and mixing rules.

Background

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Hazards

GHS pictogram: Corrosive
Corrosive (GHS05)

Attacks skin, eyes and materials.

GHS pictogram: Harmful / Irritant
Harmful / Irritant (GHS07)

May cause skin, eye or respiratory irritation.

GHS pictogram: Health hazard
Health hazard (GHS08)

Serious long-term health effects (CMR, respiratory sensitizer).

GHS pictogram: Environmental hazard
Environmental hazard (GHS09)

Toxic to aquatic organisms.

Hazard statements

  • H302
  • H312
  • H332
  • H315: Causes skin irritation [Warning Skin corrosion/irritation]
  • H319
  • H335
  • H400
  • H410
  • H412
  • H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
  • H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]
  • H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

Storage

Temperature

Keep at room temperature, below 30 °C, out of direct heat.

Ventilation

Store somewhere well-ventilated and away from any ignition source.

Containers

Metal drums or tinted glass, tightly sealed.

Keep away from

Strong acids, strong bases and powerful oxidizers.

Personal protective equipment

Gloves

Nitrile or butyl, at least 0.4 mm thick.

Eye protection

Safety goggles with side shields.

Respirator

A2 organic-vapor cartridge if the room isn't well ventilated.

Occupational exposure limits (HSE)

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EU harmonised classification (ECHA C&L)

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Transport

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FDA recalls & enforcement

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Compatibilities

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Practical safety notes

  • Corrosive. Wear chemical goggles, faceshield and chemical-resistant gloves. Have an eyewash within reach.
  • Irritant / harmful. Ventilate the workspace and avoid skin contact.
  • Serious health hazard (carcinogen, mutagen, reprotoxic, respiratory sensitizer). Substitute if possible; otherwise closed systems and medical surveillance.
  • Environmental hazard. Do not release to sewers or waterways; collect for hazardous waste disposal.

Derived from the GHS classification shown above. These notes are generic guidance and do not replace the manufacturer's SDS or your local risk assessment.

FAQ

Is 2-Nitrophenol flammable?+

2-Nitrophenol (CAS 88-75-5) does not carry the GHS02 flame pictogram in our records. Always confirm with the manufacturer's SDS section 9 (flash point) before assuming a product is non-flammable.

What PPE should I wear when handling 2-Nitrophenol?+

Chemical-splash goggles and a faceshield, chemical-resistant gloves (nitrile or butyl) and an apron are the minimum. Work inside a fume hood or use a suitable respirator. Check SDS section 8 for material-specific breakthrough times.

How should 2-Nitrophenol be stored?+

Store 2-Nitrophenol (CAS 88-75-5) in tightly closed original containers, in a cool, dry, well-ventilated area away from incompatible materials. Segregate acids from bases and keep away from metals that can be attacked.

Is 2-Nitrophenol dangerous for the environment?+

Yes. 2-Nitrophenol carries the GHS09 environment pictogram. Do not release to drains, soil or waterways; collect residues for hazardous-waste disposal in line with local regulations.

Where can I find the official Safety Data Sheet for 2-Nitrophenol?+

Official, up-to-date SDS documents are published by each manufacturer (Sigma-Aldrich, Merck, Thermo Fisher, VWR, Carl Roth, etc.) and by regulators such as ECHA and NIOSH. This page is an educational summary and does not replace the manufacturer's SDS.

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