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Chlorambucil
Also known as: chlorambucil · 305-03-3 · Chloroambucil · Ambochlorin
- CAS No.
- 305-03-3
- Formula
- C14H19Cl2NO2
- Molar mass
- 304.2 g/mol
- PubChem CID
- 2708
Toxic
Harmful / Irritant
Health hazard
Summary
Chlorambucil (C14H19Cl2NO2), CAS 305-03-3. Common in labs and industry. Read on for hazards, storage, PPE and mixing rules.
Background
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Hazards
May be fatal even in small doses.
May cause skin, eye or respiratory irritation.
Serious long-term health effects (CMR, respiratory sensitizer).
Hazard statements
- H301
- H315
- H319
- H335
- H340
- H350: May cause cancer [Danger Carcinogenicity]
- H360: May damage fertility or the unborn child [Danger Reproductive toxicity]
- H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]
- H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]
- H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
Storage
Keep at room temperature, below 30 °C, out of direct heat.
Store somewhere well-ventilated and away from any ignition source.
Metal drums or tinted glass, tightly sealed.
Strong acids, strong bases and powerful oxidizers.
Personal protective equipment
Nitrile or butyl, at least 0.4 mm thick.
Safety goggles with side shields.
A2 organic-vapor cartridge if the room isn't well ventilated.
Occupational exposure limits (HSE)
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EU harmonised classification (ECHA C&L)
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Transport
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FDA recalls & enforcement
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Compatibilities
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Open comparator with ChlorambucilPractical safety notes
- Acute toxicity. Work under a fume hood, restrict access, keep a specific antidote plan available.
- Irritant / harmful. Ventilate the workspace and avoid skin contact.
- Serious health hazard (carcinogen, mutagen, reprotoxic, respiratory sensitizer). Substitute if possible; otherwise closed systems and medical surveillance.
Derived from the GHS classification shown above. These notes are generic guidance and do not replace the manufacturer's SDS or your local risk assessment.
FAQ
Is Chlorambucil flammable?+
Chlorambucil (CAS 305-03-3) does not carry the GHS02 flame pictogram in our records. Always confirm with the manufacturer's SDS section 9 (flash point) before assuming a product is non-flammable.
What PPE should I wear when handling Chlorambucil?+
Safety glasses with side shields and nitrile gloves are the baseline. Work inside a fume hood or use a suitable respirator. Check SDS section 8 for material-specific breakthrough times.
How should Chlorambucil be stored?+
Store Chlorambucil (CAS 305-03-3) in tightly closed original containers, in a cool, dry, well-ventilated area away from incompatible materials.
Is Chlorambucil dangerous for the environment?+
No specific environmental pictogram (GHS09) is listed in our records for Chlorambucil, but any chemical waste should be handled through your site's hazardous-waste procedure, not poured down the drain.
Where can I find the official Safety Data Sheet for Chlorambucil?+
Official, up-to-date SDS documents are published by each manufacturer (Sigma-Aldrich, Merck, Thermo Fisher, VWR, Carl Roth, etc.) and by regulators such as ECHA and NIOSH. This page is an educational summary and does not replace the manufacturer's SDS.
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