Educational content for trained professionals. Not a Safety Data Sheet, not medical advice. In an emergency, call your local poison control or emergency services immediately. Terms of use.
Cyclophosphamide
Also known as: cyclophosphamide · 50-18-0 · Cytoxan · Cyclophosphamid
- CAS No.
- 50-18-0
- Formula
- C7H15Cl2N2O2P
- Molar mass
- 261.08 g/mol
- PubChem CID
- 2907
Corrosive
Toxic
Harmful / Irritant
Health hazard
Summary
Cyclophosphamide (C7H15Cl2N2O2P), CAS 50-18-0. Common in labs and industry. Read on for hazards, storage, PPE and mixing rules.
Background
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Hazards
Attacks skin, eyes and materials.
May be fatal even in small doses.
May cause skin, eye or respiratory irritation.
Serious long-term health effects (CMR, respiratory sensitizer).
Hazard statements
- H301: Toxic if swallowed [Danger Acute toxicity, oral]
- H302
- H318
- H340: May cause genetic defects [Danger Germ cell mutagenicity]
- H350: May cause cancer [Danger Carcinogenicity]
- H360: May damage fertility or the unborn child [Danger Reproductive toxicity]
- H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
- H362: May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation]
- H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]
Storage
Keep at room temperature, below 30 °C, out of direct heat.
Store somewhere well-ventilated and away from any ignition source.
Metal drums or tinted glass, tightly sealed.
Strong acids, strong bases and powerful oxidizers.
Personal protective equipment
Nitrile or butyl, at least 0.4 mm thick.
Safety goggles with side shields.
A2 organic-vapor cartridge if the room isn't well ventilated.
Occupational exposure limits (HSE)
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EU harmonised classification (ECHA C&L)
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Transport
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FDA recalls & enforcement
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Compatibilities
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Open comparator with CyclophosphamidePractical safety notes
- Corrosive. Wear chemical goggles, faceshield and chemical-resistant gloves. Have an eyewash within reach.
- Acute toxicity. Work under a fume hood, restrict access, keep a specific antidote plan available.
- Irritant / harmful. Ventilate the workspace and avoid skin contact.
- Serious health hazard (carcinogen, mutagen, reprotoxic, respiratory sensitizer). Substitute if possible; otherwise closed systems and medical surveillance.
Derived from the GHS classification shown above. These notes are generic guidance and do not replace the manufacturer's SDS or your local risk assessment.
FAQ
Is Cyclophosphamide flammable?+
Cyclophosphamide (CAS 50-18-0) does not carry the GHS02 flame pictogram in our records. Always confirm with the manufacturer's SDS section 9 (flash point) before assuming a product is non-flammable.
What PPE should I wear when handling Cyclophosphamide?+
Chemical-splash goggles and a faceshield, chemical-resistant gloves (nitrile or butyl) and an apron are the minimum. Work inside a fume hood or use a suitable respirator. Check SDS section 8 for material-specific breakthrough times.
How should Cyclophosphamide be stored?+
Store Cyclophosphamide (CAS 50-18-0) in tightly closed original containers, in a cool, dry, well-ventilated area away from incompatible materials. Segregate acids from bases and keep away from metals that can be attacked.
Is Cyclophosphamide dangerous for the environment?+
No specific environmental pictogram (GHS09) is listed in our records for Cyclophosphamide, but any chemical waste should be handled through your site's hazardous-waste procedure, not poured down the drain.
Where can I find the official Safety Data Sheet for Cyclophosphamide?+
Official, up-to-date SDS documents are published by each manufacturer (Sigma-Aldrich, Merck, Thermo Fisher, VWR, Carl Roth, etc.) and by regulators such as ECHA and NIOSH. This page is an educational summary and does not replace the manufacturer's SDS.
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