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Isopropyl chloroacetate
Also known as: ISOPROPYL CHLOROACETATE · 105-48-6 · Chloroacetic acid isopropyl ester · Acetic acid, chloro-, 1-methylethyl ester
- CAS No.
- 105-48-6
- Formula
- C5H9ClO2
- Molar mass
- 136.58 g/mol
- PubChem CID
- 7759
Flammable
Toxic
Harmful / Irritant
Summary
Isopropyl chloroacetate (C5H9ClO2), CAS 105-48-6. Common in labs and industry. Read on for hazards, storage, PPE and mixing rules.
Background
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Hazards
Ignites easily when exposed to a flame or spark.
May be fatal even in small doses.
May cause skin, eye or respiratory irritation.
Hazard statements
- H226: Flammable liquid and vapor [Warning Flammable liquids]
- H301: Toxic if swallowed [Danger Acute toxicity, oral]
- H315: Causes skin irritation [Warning Skin corrosion/irritation]
- H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure
- H300: Fatal if swallowed [Danger Acute toxicity, oral]
- H331: Toxic if inhaled [Danger Acute toxicity, inhalation]
Storage
Keep at room temperature, below 30 °C, out of direct heat.
Store somewhere well-ventilated and away from any ignition source.
Metal drums or tinted glass, tightly sealed.
Strong acids, strong bases and powerful oxidizers.
Personal protective equipment
Nitrile or butyl, at least 0.4 mm thick.
Safety goggles with side shields.
A2 organic-vapor cartridge if the room isn't well ventilated.
Occupational exposure limits (HSE)
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EU harmonised classification (ECHA C&L)
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Transport
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FDA recalls & enforcement
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Compatibilities
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Open comparator with Isopropyl chloroacetatePractical safety notes
- Flammable. Keep away from open flames, hot surfaces and sparks. Ground containers when transferring.
- Acute toxicity. Work under a fume hood, restrict access, keep a specific antidote plan available.
- Irritant / harmful. Ventilate the workspace and avoid skin contact.
Derived from the GHS classification shown above. These notes are generic guidance and do not replace the manufacturer's SDS or your local risk assessment.
FAQ
Is Isopropyl chloroacetate flammable?+
Yes. Isopropyl chloroacetate (CAS 105-48-6) carries the GHS02 flame pictogram. Keep it away from ignition sources, use non-sparking tools, and ground metal containers when transferring liquid.
What PPE should I wear when handling Isopropyl chloroacetate?+
Safety glasses with side shields and nitrile gloves are the baseline. Work inside a fume hood or use a suitable respirator. Check SDS section 8 for material-specific breakthrough times.
How should Isopropyl chloroacetate be stored?+
Store Isopropyl chloroacetate (CAS 105-48-6) in tightly closed original containers, in a cool, dry, well-ventilated area away from incompatible materials. Use a flammable-liquid cabinet and keep away from oxidizers and heat.
Is Isopropyl chloroacetate dangerous for the environment?+
No specific environmental pictogram (GHS09) is listed in our records for Isopropyl chloroacetate, but any chemical waste should be handled through your site's hazardous-waste procedure, not poured down the drain.
Where can I find the official Safety Data Sheet for Isopropyl chloroacetate?+
Official, up-to-date SDS documents are published by each manufacturer (Sigma-Aldrich, Merck, Thermo Fisher, VWR, Carl Roth, etc.) and by regulators such as ECHA and NIOSH. This page is an educational summary and does not replace the manufacturer's SDS.
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