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Midazolam

Also known as: midazolam · 59467-70-8 · Buccolam · Midazolamum

CAS No.
59467-70-8
Formula
C18H13ClFN3
Molar mass
325.8 g/mol
PubChem CID
4192
GHS pictograms
GHS pictogram: ToxicToxic
GHS pictogram: Harmful / IrritantHarmful / Irritant
GHS pictogram: Health hazardHealth hazard
GHS pictogram: Environmental hazardEnvironmental hazard
2D structure of Midazolam
2D structure · PubChem CID 4192

Summary

Midazolam (C18H13ClFN3), CAS 59467-70-8. Common in labs and industry. Read on for hazards, storage, PPE and mixing rules.

Background

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Physical properties

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Hazards

GHS pictogram: Toxic
Toxic (GHS06)

May be fatal even in small doses.

GHS pictogram: Harmful / Irritant
Harmful / Irritant (GHS07)

May cause skin, eye or respiratory irritation.

GHS pictogram: Health hazard
Health hazard (GHS08)

Serious long-term health effects (CMR, respiratory sensitizer).

GHS pictogram: Environmental hazard
Environmental hazard (GHS09)

Toxic to aquatic organisms.

Storage

Temperature

Keep at room temperature, below 30 °C, out of direct heat.

Ventilation

Store somewhere well-ventilated and away from any ignition source.

Containers

Metal drums or tinted glass, tightly sealed.

Keep away from

Strong acids, strong bases and powerful oxidizers.

Personal protective equipment

Gloves

Nitrile or butyl, at least 0.4 mm thick.

Eye protection

Safety goggles with side shields.

Respirator

A2 organic-vapor cartridge if the room isn't well ventilated.

Occupational exposure limits (HSE)

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EU harmonised classification (ECHA C&L)

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Transport

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FDA recalls & enforcement

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Compatibilities

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Practical safety notes

  • Acute toxicity. Work under a fume hood, restrict access, keep a specific antidote plan available.
  • Irritant / harmful. Ventilate the workspace and avoid skin contact.
  • Serious health hazard (carcinogen, mutagen, reprotoxic, respiratory sensitizer). Substitute if possible; otherwise closed systems and medical surveillance.
  • Environmental hazard. Do not release to sewers or waterways; collect for hazardous waste disposal.

Derived from the GHS classification shown above. These notes are generic guidance and do not replace the manufacturer's SDS or your local risk assessment.

FAQ

Is Midazolam flammable?+

Midazolam (CAS 59467-70-8) does not carry the GHS02 flame pictogram in our records. Always confirm with the manufacturer's SDS section 9 (flash point) before assuming a product is non-flammable.

What PPE should I wear when handling Midazolam?+

Safety glasses with side shields and nitrile gloves are the baseline. Work inside a fume hood or use a suitable respirator. Check SDS section 8 for material-specific breakthrough times.

How should Midazolam be stored?+

Store Midazolam (CAS 59467-70-8) in tightly closed original containers, in a cool, dry, well-ventilated area away from incompatible materials.

Is Midazolam dangerous for the environment?+

Yes. Midazolam carries the GHS09 environment pictogram. Do not release to drains, soil or waterways; collect residues for hazardous-waste disposal in line with local regulations.

Where can I find the official Safety Data Sheet for Midazolam?+

Official, up-to-date SDS documents are published by each manufacturer (Sigma-Aldrich, Merck, Thermo Fisher, VWR, Carl Roth, etc.) and by regulators such as ECHA and NIOSH. This page is an educational summary and does not replace the manufacturer's SDS.

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