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Quetiapine

Also known as: quetiapine · 111974-69-7 · quetiapina · Norsic

CAS No.
111974-69-7
Formula
C21H25N3O2S
Molar mass
383.5 g/mol
PubChem CID
5002
GHS pictograms
GHS pictogram: FlammableFlammable
GHS pictogram: CorrosiveCorrosive
GHS pictogram: ToxicToxic
GHS pictogram: Harmful / IrritantHarmful / Irritant
GHS pictogram: Health hazardHealth hazard
GHS pictogram: Environmental hazardEnvironmental hazard
2D structure of Quetiapine
2D structure · PubChem CID 5002

Summary

Quetiapine (C21H25N3O2S), CAS 111974-69-7. Common in labs and industry. Read on for hazards, storage, PPE and mixing rules.

Background

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Hazards

GHS pictogram: Flammable
Flammable (GHS02)

Ignites easily when exposed to a flame or spark.

GHS pictogram: Corrosive
Corrosive (GHS05)

Attacks skin, eyes and materials.

GHS pictogram: Toxic
Toxic (GHS06)

May be fatal even in small doses.

GHS pictogram: Harmful / Irritant
Harmful / Irritant (GHS07)

May cause skin, eye or respiratory irritation.

GHS pictogram: Health hazard
Health hazard (GHS08)

Serious long-term health effects (CMR, respiratory sensitizer).

GHS pictogram: Environmental hazard
Environmental hazard (GHS09)

Toxic to aquatic organisms.

Hazard statements

  • H302
  • H318
  • H335
  • H400
  • H410
  • H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
  • H225: Highly Flammable liquid and vapor [Danger Flammable liquids]
  • H301: Toxic if swallowed [Danger Acute toxicity, oral]
  • H311: Toxic in contact with skin [Danger Acute toxicity, dermal]
  • H331: Toxic if inhaled [Danger Acute toxicity, inhalation]
  • H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]
  • H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]

Storage

Temperature

Keep at room temperature, below 30 °C, out of direct heat.

Ventilation

Store somewhere well-ventilated and away from any ignition source.

Containers

Metal drums or tinted glass, tightly sealed.

Keep away from

Strong acids, strong bases and powerful oxidizers.

Personal protective equipment

Gloves

Nitrile or butyl, at least 0.4 mm thick.

Eye protection

Safety goggles with side shields.

Respirator

A2 organic-vapor cartridge if the room isn't well ventilated.

Occupational exposure limits (HSE)

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EU harmonised classification (ECHA C&L)

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Transport

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FDA recalls & enforcement

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Compatibilities

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Practical safety notes

  • Flammable. Keep away from open flames, hot surfaces and sparks. Ground containers when transferring.
  • Corrosive. Wear chemical goggles, faceshield and chemical-resistant gloves. Have an eyewash within reach.
  • Acute toxicity. Work under a fume hood, restrict access, keep a specific antidote plan available.
  • Irritant / harmful. Ventilate the workspace and avoid skin contact.
  • Serious health hazard (carcinogen, mutagen, reprotoxic, respiratory sensitizer). Substitute if possible; otherwise closed systems and medical surveillance.
  • Environmental hazard. Do not release to sewers or waterways; collect for hazardous waste disposal.

Derived from the GHS classification shown above. These notes are generic guidance and do not replace the manufacturer's SDS or your local risk assessment.

FAQ

Is Quetiapine flammable?+

Yes. Quetiapine (CAS 111974-69-7) carries the GHS02 flame pictogram. Keep it away from ignition sources, use non-sparking tools, and ground metal containers when transferring liquid.

What PPE should I wear when handling Quetiapine?+

Chemical-splash goggles and a faceshield, chemical-resistant gloves (nitrile or butyl) and an apron are the minimum. Work inside a fume hood or use a suitable respirator. Check SDS section 8 for material-specific breakthrough times.

How should Quetiapine be stored?+

Store Quetiapine (CAS 111974-69-7) in tightly closed original containers, in a cool, dry, well-ventilated area away from incompatible materials. Use a flammable-liquid cabinet and keep away from oxidizers and heat. Segregate acids from bases and keep away from metals that can be attacked.

Is Quetiapine dangerous for the environment?+

Yes. Quetiapine carries the GHS09 environment pictogram. Do not release to drains, soil or waterways; collect residues for hazardous-waste disposal in line with local regulations.

Where can I find the official Safety Data Sheet for Quetiapine?+

Official, up-to-date SDS documents are published by each manufacturer (Sigma-Aldrich, Merck, Thermo Fisher, VWR, Carl Roth, etc.) and by regulators such as ECHA and NIOSH. This page is an educational summary and does not replace the manufacturer's SDS.

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