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rotenone
Also known as: rotenone · 83-79-4 · Dactinol · Paraderil
- CAS No.
- 83-79-4
- Formula
- C23H22O6
- Molar mass
- 394.4 g/mol
- PubChem CID
- 6758
Toxic
Harmful / Irritant
Health hazard
Environmental hazard
Summary
rotenone (C23H22O6), CAS 83-79-4. Common in labs and industry. Read on for hazards, storage, PPE and mixing rules.
Background
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Physical properties
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Hazards
May be fatal even in small doses.
May cause skin, eye or respiratory irritation.
Serious long-term health effects (CMR, respiratory sensitizer).
Toxic to aquatic organisms.
Hazard statements
- H301: Toxic if swallowed [Danger Acute toxicity, oral]
- H315: Causes skin irritation [Warning Skin corrosion/irritation]
- H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure
- H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
- H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
- H300: Fatal if swallowed [Danger Acute toxicity, oral]
- H310: Fatal in contact with skin [Danger Acute toxicity, dermal]
- H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]
- H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
- H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
Storage
Keep at room temperature, below 30 °C, out of direct heat.
Store somewhere well-ventilated and away from any ignition source.
Metal drums or tinted glass, tightly sealed.
Strong acids, strong bases and powerful oxidizers.
Personal protective equipment
Nitrile or butyl, at least 0.4 mm thick.
Safety goggles with side shields.
A2 organic-vapor cartridge if the room isn't well ventilated.
Occupational exposure limits (HSE)
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EU harmonised classification (ECHA C&L)
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Transport
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FDA recalls & enforcement
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Compatibilities
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Open comparator with rotenonePractical safety notes
- Acute toxicity. Work under a fume hood, restrict access, keep a specific antidote plan available.
- Irritant / harmful. Ventilate the workspace and avoid skin contact.
- Serious health hazard (carcinogen, mutagen, reprotoxic, respiratory sensitizer). Substitute if possible; otherwise closed systems and medical surveillance.
- Environmental hazard. Do not release to sewers or waterways; collect for hazardous waste disposal.
Derived from the GHS classification shown above. These notes are generic guidance and do not replace the manufacturer's SDS or your local risk assessment.
FAQ
Is rotenone flammable?+
rotenone (CAS 83-79-4) does not carry the GHS02 flame pictogram in our records. Always confirm with the manufacturer's SDS section 9 (flash point) before assuming a product is non-flammable.
What PPE should I wear when handling rotenone?+
Safety glasses with side shields and nitrile gloves are the baseline. Work inside a fume hood or use a suitable respirator. Check SDS section 8 for material-specific breakthrough times.
How should rotenone be stored?+
Store rotenone (CAS 83-79-4) in tightly closed original containers, in a cool, dry, well-ventilated area away from incompatible materials.
Is rotenone dangerous for the environment?+
Yes. rotenone carries the GHS09 environment pictogram. Do not release to drains, soil or waterways; collect residues for hazardous-waste disposal in line with local regulations.
Where can I find the official Safety Data Sheet for rotenone?+
Official, up-to-date SDS documents are published by each manufacturer (Sigma-Aldrich, Merck, Thermo Fisher, VWR, Carl Roth, etc.) and by regulators such as ECHA and NIOSH. This page is an educational summary and does not replace the manufacturer's SDS.
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